RESEARCH SCIENTIST / SR RESEARCH SCIENTIST -DRUG DISCOVERY (R&D) -NCES (03 VACANCIES) @ BACHWELL PHARMA
Bachwell Pharma is seeking highly skilled professionals for the role of Research Scientist and Senior Research Scientist within the Drug Discovery and Research & Development department. The focus of this role is on early-stage process research and the synthesis of Novel Chemical Entities (NCEs). Candidates will be responsible for new molecule design, lead generation, and medicinal chemistry, utilizing Structure-Activity Relationship (SAR) methods to systematically modify molecules for improved potency, stability, and safety. This position is based at the Pashamylaram IDA facility in Hyderabad.
The role involves a high level of technical expertise and cross-functional collaboration. Researchers will conduct rational drug design using Computer-Aided Drug Design (CADD) and molecular docking techniques. Additionally, the position entails advanced analytics and structural elucidation using high-end instrumentation like 600 MHz NMR and LC-MS/MS. Successful candidates will also manage impurity profiling and work closely with pharmacology and pharmacokinetics teams to translate chemical discoveries into potential drug candidates while documenting all findings for intellectual property and patent support.
The role involves a high level of technical expertise and cross-functional collaboration. Researchers will conduct rational drug design using Computer-Aided Drug Design (CADD) and molecular docking techniques. Additionally, the position entails advanced analytics and structural elucidation using high-end instrumentation like 600 MHz NMR and LC-MS/MS. Successful candidates will also manage impurity profiling and work closely with pharmacology and pharmacokinetics teams to translate chemical discoveries into potential drug candidates while documenting all findings for intellectual property and patent support.
Key Requirements
M.Sc, M.Tech, or Ph.D. in Organic Chemistry.
Between 2 to 12 years of relevant experience in R&D and drug discovery.
Expertise in synthesizing novel chemical entities (NCEs) from scratch.
In-depth knowledge of Structure-Activity Relationship (SAR) modifications.
Proficiency in rational drug design using CADD and molecular docking.
Ability to develop chemical scaffolds for library compound synthesis.
Experience in conducting feasibility studies for synthetic pathways.
Knowledge of non-infringing route scouting to avoid existing patents.
Proficiency with 600 MHz NMR, LC-MS/MS, and HRMS for structural elucidation.
Capability to identify and profile mutagenic impurities during discovery.
Strong documentation skills for maintaining Electronic Lab Notebooks (ELN).
Ability to collaborate effectively with pharmacology and ADME teams.